Vivaspin® 500 Centrifugal Concentrator Polyethersulfone, 3 kDa (25 pieces/pack)

The Vivaspin® 500 Centrifugal Concentrator represents a standard for rapid concentration and diafiltration of small proteins, peptides and other macromolecules in sample volumes up to 500 µL. Featuring innovative crossflow technology with a vertical polyethersulfone (PES) membrane design, this disposable ultrafiltration unit delivers unparalleled filtration speed while avoiding membrane fouling that commonly affects traditional dead-end filtration systems. The high-flux PES membrane typically achieves greater than 90% sample recovery in less than 30 minutes, making it ideal for time-sensitive applications and high-throughput workflows in pharmaceutical, biotechnology and life science research environments.

Available in convenient 25-unit packs, it enables concentration factors up to 100-fold while eliminating the risk of sample loss and simplifying retentate retrieval with standard laboratory pipettes. The device features convenient volume graduations on both the concentrator housing and filtrate tube, allowing researchers to easily monitor ultrafiltration progress and precisely control concentration levels. The 0.5 cm² membrane area and optimized geometry ensure efficient processing while maintaining gentle handling of sensitive samples including proteins, viruses, nucleic acids, nanoparticles and viral vectors.

Constructed from high-quality polycarbonate and polypropylene materials with ISO 9001 certification, each concentrator offers exceptional chemical compatibility and reliability for demanding laboratory applications. The 3 kDa molecular weight cut-off makes this device particularly suitable for concentrating small proteins, large peptides, and oligonucleotides while effectively removing salts, buffers and other small molecules during desalting and buffer exchange procedures.

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