Hamilton Column PRP-3 10 µm, 7.0 x 305 mm

Hamilton PRP-3 columns are based on the PRP-1 with a larger pore size for the separation of macromolecules such as DNA, RNA oligos, proteins, peptides, and proteomics. This column resin has no silanol groups, so irreversible protein adsorption is not a concern, giving analytes such as proteins a recovery of > 90%. This stable material also allows the use of concentrated acids, chaotropes, and even detergents to minimize problems with protein solubility.